NCT-504

• Description:

  NCT-504 is a selective allosteric inhibitor of PIP4Kγ, with an IC50 of 15.8 μM. NCT-504 is potential for the research of Huntington's disease[1].

• UNSPSC:

  12352005

• Target:

  PI5P4K

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nct-504.html

• Purity:

  99.46

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  CN1N=NN=C1SC2=C (C (C3=CC=CC (S (=O) (C) =O) =C3) =CS4) C4=NC=N2

• Molecular Formula:

  C15H12N6O2S3

• Molecular Weight:

  404.49

• References & Citations:

  [1]Ismael Al-Ramahi, et al. Inhibition of PIP4Kγ Ameliorates the Pathological Effects of Mutant Huntingtin Protein. Elife. 2017 Dec 26;6:e29123.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1222765-97-0