Products for Research Use Only
RegisterLogin

KZR-504

CAT: 0804-HY-101786-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101786-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 is of interest for the treatment of autoimmune disease[1].
CAS Number
1629052-78-3
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/KZR-504.html
Purity
99.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C([C@]2(CO2)C)=O)=O)C(N3)=CC=CC3=O
Molecular Formula
C21H23N3O6
Molecular Weight
413.42
References & Citations
[1]Johnson HWB, et al. Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit. ACS Med Chem Lett. 2017 Mar 9;8 (4) :413-417.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-176763KZR-261
HY-136311-01NCT-504
HY-W953284CRBN ligand-504
HY-129759KSG-504 (anhydrous)
HY-R04502-01Rno-miR-504 mimic
HY-RI04502A-01Rno-miR-504 antagomir
HY-R04502A-01Rno-miR-504 agomir
HY-RI04502-01Rno-miR-504 inhibitor
HY-RI03238-01Mmu-miR-504-3p inhibitor
HY-R03238-01Mmu-miR-504-3p mimic

Alternative Products

CatalogName
BA8286-10KZR-504
A19210-50KZR-504 50mg
A19210-1KZR-504 1mg
A19210-5KZR-504 5mg
A19210-100KZR-504 100mg
A19210-25KZR-504 25mg
A19210-10KZR-504 10mg
GTR19264231-01KZR-261
MBS3602445-01KZR-616
M35051-01NCT-504

Popular Products