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NCT-504

CAT: 0804-HY-136311-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136311-01Size:5 mg
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Description
NCT-504 is a selective allosteric inhibitor of PIP4Kγ, with an IC50 of 15.8 μM. NCT-504 is potential for the research of Huntington's disease[1].
CAS Number
1222765-97-0
UNSPSC
12352005
Target
PI5P4K
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nct-504.html
Purity
99.46
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN1N=NN=C1SC2=C(C(C3=CC=CC(S(=O)(C)=O)=C3)=CS4)C4=NC=N2
Molecular Formula
C15H12N6O2S3
Molecular Weight
404.49
References & Citations
[1]Ismael Al-Ramahi, et al. Inhibition of PIP4Kγ Ameliorates the Pathological Effects of Mutant Huntingtin Protein. Elife. 2017 Dec 26;6:e29123.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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