SDZ281-977

• Description:

  SDZ 281-977 is a derivative of the EGF receptor tyrosine kinase inhibitor Lavendustin A.

• Product Name Alternative:

  SDZ-LAP 977

• UNSPSC:

  12352005

• Target:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/SDZ281-977.html

• Purity:

  98.00

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC)C1=CC(CCC2=CC(OC)=CC=C2OC)=CC=C1O

• Molecular Formula:

  C18H20O5

• Molecular Weight:

  316.35

• References & Citations:

  [1]Cammisuli S, et al. SDZ 281-977: a modified partial structure of lavendustin A that exerts potent and selective antiproliferative activities in vitro and in vivo. Int J Cancer. 1996 Jan 26;65 (3) :351-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [150779-71-8]