BAY-u 9773

• Description:

  BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Leukotriene Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bay-u-9773.html

• Concentration:

  211.58 μM * 250 μL in Ethanol

• Purity:

  95.5

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC1=CC=C(C=C1)C(O)=O)=O

• Molecular Formula:

  C27H36O5S

• Molecular Weight:

  472.64

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Tudhope SR, et al. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. Eur J Pharmacol. 1994 Nov 3;264 (3) :317-23.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C, protect from light

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  LTC4/CysLT2; LTD4/CysLT1

• CAS Number:

  [154978-38-8]