Products for Research Use Only
RegisterLogin

GSK-9772

CAT: 0804-HY-14353Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14353Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GSK-9772 is a Liver X Receptor (LXR) modulator of the N-phenyl tertiary amine class (NPTAs) with high affinity for LXR β ligand (IC50=30 nM) . GSK-9772 has anti-inflammatory activity by binding to LXR, specifically by interacting with the region associated with the transcriptional repression function of the receptor, thereby inhibiting the expression of pro-inflammatory genes. GSK-9772 can be used in the study of inflammatory and neurodegenerative diseases[1].
CAS Number
928035-84-1
UNSPSC
12352005
Target
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk-9772.html
Smiles
OC1=C(Cl)C=C(CN(CCCC)C2=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C2)C=C1Cl
Molecular Formula
C20H19Cl2F6NO2
Molecular Weight
490.27
References & Citations
[1]EY Chao, et al. Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. Journal of medicinal chemistry 51.18 (2008) : 5758-5765.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P991051-01GSK-2330811
HY-P990592-01GSK-3050002
HY-108081GSK-958108
HY-117658-01GSK-114
HY-15192-01GSK 650394
HY-18665-01GSK-5959
HY-121594GSK-269984B
HY-15648-01GSK-J1
HY-33353-01GSK-4716
HY-100186-01GSK-2881078

Alternative Products

CatalogName
T25471-01GSK-A
TL311972VKIAA0195 (TMEM94) Human shRNA Lentiviral Particle (Locus ID 9772)
MBS131437GSK163090 (GSK-163090; GSK 163090)
MBS131519GSK369796 (GSK-369796, GSK 369796)
TL311972KIAA0195 (TMEM94) Human shRNA Plasmid Kit (Locus ID 9772)
SR306534KIAA0195 (TMEM94) Human siRNA Oligo Duplex (Locus ID 9772)
A3450-5.1GSK-923295
BA4485-5.1GSK-25
B7751-100GSK 2193874
A3445-5.1GSK 525768A

Popular Products