Products for Research Use Only
RegisterLogin

GS-9770

CAT: 0804-HY-162525Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162525Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GS-9770 is an orally active inhibitor for HIV protease with Ki of 0.16 nM. GS-9770 exhibits antiviral activity aginst HIV-1 strains and HIV-2 strains with EC50 of 1.9-26 nM, and 26 nM. GS-9770 is metabolic stable in human liver microsomes. GS-9770 exhibits good pharmacokinetic characters in Sprague Dawley rats[1].
CAS Number
2306328-43-6
UNSPSC
12352005
Target
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gs-9770.html
Smiles
CC(C(F)(F)F)(C[C@@]1(C2=CC=C(C=C2)C3=NN(N=C3)C4CC4)C(N(C(N1)=N)[C@@H](C5=CC=C(C(C6=NC=NN6C(F)F)=C5)Cl)COC(NC7(C(F)F)CC7)=O)=O)C
Molecular Formula
C35H34ClF7N10O3
Molecular Weight
811.15
References & Citations
[1]Mulato A, et al., Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability. Antimicrob Agents Chemother. 2024 Apr 3;68 (4) :e0137323.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P991479GS-8588
HY-145713GS-8873
HY-120159GS-493
HY-161877GS-7682
HY-114416-01GS-626510
HY-159983-01GS-2278
HY-122229GS-9822
HY-100694-01GS-9901
HY-176707GS​​K2181306A
HY-10081-01GS-6201

Alternative Products

CatalogName
T88206-01GS-9770
TL302096RASSF2 Human shRNA Plasmid Kit (Locus ID 9770)
TL302096VRASSF2 Human shRNA Lentiviral Particle (Locus ID 9770)
SR306532RASSF2 Human siRNA Oligo Duplex (Locus ID 9770)
MBS131349Selonsertib (GS-4997; GS4997; GS 4997)
B8021-5GS-7340
BA7317-1GS-704277
BA4730-25GS-626510
B8461-50GS-441524
BA8760-5GS-9901

Popular Products