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(R) -DM4-SPDP

CAT: 0804-HY-126493ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126493ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates[1].
CAS Number
2245698-48-8
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-dm4-spdp.html
Smiles
C[C@]1([C@H](CC(N(C(C=C(C2)C=C3OC)=C3Cl)C)=O)OC([C@@H](C)N(C)C(CCC(C)(C)SSCCC(ON(C4=O)C(CC4)=O)=O)=O)=O)[C@@]([C@@H]([C@](OC5=O)([H])C[C@]([C@@H](/C=C/C=C2\C)OC)(N5)O)C)([H])O1
Molecular Formula
C45H61ClN4O14S2
Molecular Weight
981.57
References & Citations
[1]Silvana T Tivadar, et al. Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther. 2020 Mar;19 (3) :790-801.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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