PEG4-SPDP

• Description:

  PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs) .

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/peg4-spdp.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCSSC2=NC=CC=C2

• Molecular Formula:

  C20H28N2O8S2

• Molecular Weight:

  488.57

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54 (10) :3606-23.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker; Disulfide Cleavable Linker

• CAS Number:

  [1305053-43-3]