PEG4-SPDP

• Description :

  PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs) .

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/peg4-spdp.html

• Purity :

  98.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCSSC2=NC=CC=C2

• Molecular Formula :

  C20H28N2O8S2

• Molecular Weight :

  488.57

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54 (10) :3606-23.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Cleavable Linker; Disulfide Cleavable Linker

• CAS Number :

  [1305053-43-3]