Sarafotoxin S6d

• Description:

  Sarafotoxin S6d (STX-b) is a polypeptide toxin isolated from the venom of the Israeli sand boa constrictor. Sarafotoxin S6d induces multiple electrocardiogram (ECG) changes including myocardial ischemia and hyperkalemia. Sarafotoxin S6d induces strong extracellular calcium-dependent vasoconstriction in rat aorta and exhibits positive inotropic effects in rat atria. Sarafotoxin S6d can be used in the study of cardiovascular diseases[1].

• Product Name Alternative:

  STX-b

• UNSPSC:

  12352209

• Target:

  Calcium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sarafotoxin-s6d.html

• Smiles:

  O=C ([C@@H] (N) CSSC[C@H] (NC1=O) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (O) =O) CC2=CNC3=CC=CC=C23) =O) [C@H] (CC) C) =O) [C@H] (CC) C) =O) CC (O) =O) =O) CCC (N) =O) =O) CC4=CNC=N4) =O) N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H]5CCC (O) =O) =O) CCCCN) =O) CC (O) =O) =O) [C@@H] (C) O) =O) CCSC) =O) CC (O) =O) =O) CCCCN) =O) CSSC[C@H] (NC5=O) C (N[C@H] (C (N[C@H] (C (N[C@H]1CC6=CC=CC=C6) =O) CC7=CC=C (O) C=C7) =O) CC (C) C) =O) =O) [C@@H] (C) O

• Molecular Formula:

  C112H163N27O34S5

• Molecular Weight:

  2591.98

• References & Citations:

  [1]Lin W W, et al. Cardiovascular effects of two disulfide analogues of sarafotoxin S6b[J]. Toxicon, 1990, 28 (8) : 911-923.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  1446991-36-1