Sarafotoxin S6c

Sarafotoxin S6c

• CAS Number: 121695-87-2
• UNSPSC Description: Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].
• Target Antigen: Endothelin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/sarafotoxin-s6c.html
• Purity: 98.19
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]2([H])NC([C@@H](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@](CSSC2)([H])NC([C@](NC([C@H](CSSC1)N)=O)([H])[C@H](O)C)=O)=O)CC(N)=O)=O)CC(O)=O)=O)CCSC)=O)([H])[C@H](O)C)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC3=CC=CC=C3)=O)N[C@@H](CC4=CN=CN4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O
• Molecular Weight: 2515.75
• References & Citations: [1]MacLean MR, et al. Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries. J Cardiovasc Pharmacol. 1995 Nov;26(5):822-30.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported