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Sarafotoxin S6a

CAT: 0804-HY-P1112-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1112-01Size:1 mg
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Description
Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3. Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM[1].
CAS Number
126738-34-9
UNSPSC
12352209
Hazard Statement
H301, H311, H330
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sarafotoxin-s6a.html
Purity
98.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@]4(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CSSC2)(CSSC4)[H])[H])[H])=O)CCC(N)=O)=O)CC(O)=O)=O)[C@H](C)C)=O)[C@H](CC)C)=O)C(O)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C105H156N28O34S5
Molecular Weight
2514.85
Precautions
H301, H311, H330
References & Citations
[1]P Schoeffter, et al. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur J Pharmacol
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
ETA; ETB

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