MK 319

• Description :

  MK 319 is a selective aldose reductase (AR) inhibitor with an IC50 of 0.3 μM. MK 319 can be utilized in diabetes research[1].

• UNSPSC :

  12352005

• Target :

  Aldose Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/mk-319.html

• Smiles :

  O=C(C1=CC=C(C=C1OCC(O)=O)Cl)NCC2=C(C(F)=C(C(F)=C2F)Br)F

• Molecular Formula :

  C16H9BrClF4NO4

• Molecular Weight :

  470.60

• References & Citations :

  [1]Cousido-Siah A, et al. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. ACS Chem Biol. 2016 Oct 21;11 (10) :2693-2705.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1462383-00-1]