MK 319

• UNSPSC Description:

  MK 319 is a selective aldose reductase (AR) inhibitor with an IC50 of 0.3 μM. MK 319 can be utilized in diabetes research[1].

• Target Antigen:

  Aldose Reductase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/mk-319.html

• Smiles:

  O=C(C1=CC=C(C=C1OCC(O)=O)Cl)NCC2=C(C(F)=C(C(F)=C2F)Br)F

• Molecular Weight:

  470.60

• References & Citations:

  [1]Cousido-Siah A, et al. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1462383-00-1