(R) -SLV 319

• Description:

  (R) -SLV 319 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki value of 894 nM. (R) -SLV 319 is a dextrorotatory counterpart of SLV 319[1]

• UNSPSC:

  12352005

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/r-slv-319.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/N=C (N1N=C (C2=CC=C (Cl) C=C2) [C@H] (C3=CC=CC=C3) C1) /NS (=O) (C4=CC=C (Cl) C=C4) =O

• Molecular Formula:

  C23H20Cl2N4O2S

• Molecular Weight:

  487.40

• References & Citations:

  [1]Lange JH, et al. Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB (1) cannabinoid receptor antagonists. J Med Chem. 2004;47 (3) :627-643.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB1

• CAS Number:

  656827-86-0