ELA-11(human)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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ELA-11(human)

CAT:

804-HY-P2197-01

Size:

5 mg

Price:

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For price, please contact [email protected].

CAS Number: 1784687-32-6
UNSPSC Description: ELA-11(human), a peptide, is a full agonist of human apelin receptor, with a pKi of 7.85. ELA-11(human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment[1].
Target Antigen: Apelin Receptor (APJ); Arrestin
Type: Peptides
Related Pathways: GPCR/G Protein
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/ela-11-human.html
Purity: 99.03
Solubility: H2O : 100 mg/mL (ultrasonic)
Smiles: O=C(N1[C@@H](CCC1)C(O)=O)[C@H](CC2=CC=CC=C2)NC([C@H]3N(CCC3)C([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@H](CC(C)C)NC([C@H]4N(CCC4)C([C@H](CCSC)NC([C@@H](N)CS)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O
Molecular Weight: 1283.56
References & Citations: [1]Yang P, et, al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017 Mar 21;135(12):1160-1173.
Shipping Conditions: Blue Ice
Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Clinical Information: No Development Reported

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Our range of products, including ELA-11(human), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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Cat	Name
HY-P2197-03	ELA-11(human)
HY-P2197-01	ELA-11(human)
HY-P2197-02	ELA-11(human)
HY-P2197A-03	ELA-11(human) (TFA)
HY-P2197A-02	ELA-11(human) (TFA)
HY-P2197A-01	ELA-11(human) (TFA)
HY-P2249-02	ELA-21 (human)
HY-P2249-03	ELA-21 (human)
HY-P2249-01	ELA-21 (human)
HY-P2196-03	ELA-32(human)