ELA-11 (human)

• Target:

  Apelin receptor|||Arrestin

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  High affinity apelin receptor agonist (Ki = 14 nM) . Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates ?-arrestin recruitment in vitro.

• Smiles:

  C (N[C@H] (C (=O) N1[C@H] (C (O) =O) CCC1) CC2=CC=CC=C2) (=O) [C@H]3N (C ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC4=CN=CN4) NC ([C@@H] (NC (=O) [C@H]5N (C ([C@@H] (NC ([C@H] (CS) N) =O) CCSC) =O) CCC5) CC (C) C) =O) =O) CO) =O) CCCNC (=N) N) =O) [C@@H] (C) C) =O) CCC3

• Molecular Formula:

  C58H90N16O13S2

• Molecular Weight:

  1283.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1784687-32-6