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ELA-11 (human) (TFA)

CAT: 0804-HY-P2197A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2197A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ELA-11 (human) TFA is a high affinity apelin receptor agonist (Ki=14 nM) . ELA-11 (human) TFA is a bioactive fragment of ELA-32. ELA-11 (human) TFA inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
UNSPSC
12352209
Target
Apelin Receptor (APJ)
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ela-11-human-tfa.html
Purity
99.03
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.O=C(N1[C@@H](CCC1)C(O)=O)[C@H](CC2=CC=CC=C2)NC([C@H]3N(CCC3)C([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@H](CC(C)C)NC([C@H]4N(CCC4)C([C@H](CCSC)NC([C@@H](N)CS)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O
Molecular Formula
C60H91F3N16O15S2
Molecular Weight
1397.58
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported