Products for Research Use Only
RegisterLogin

Antiangiogenic agent 7

CAT: 0804-HY-168300Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-168300Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antiangiogenic agent 7 (Compound 1) can induce cell apoptosis, increase Reactive Oxygen Species, and inhibit the intracellular enzyme thioredoxin reductase. Antiangiogenic agent 7 has anti-cancer activity, with an IC50 of 0.08-3.5 μM against cervical cancer cells HeLa, prostate cancer cells PC-3, and non-small cell lung cancer A549. Antiangiogenic agent 7 inhibits tumor growth in mouse xenograft models[1].
CAS Number
2527888-07-7
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antiangiogenic-agent-7.html
Smiles
S=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=C([Au][P@@]4(C5)CN(C6)C[N@]5C[N@@]6C4)C=CC=C3
Molecular Formula
C24H26AuN3P2S
Molecular Weight
647.46
References & Citations
[1]T. Srinivasa Reddy, et al. Gold (I) complexes of the type [AuL{κC-2-C6H4P (S) Ph2}] [L = PTA, PPh3, PPh2 (C6H4-3-SO3Na) and PPh2 (2-py) ]: Synthesis, characterisation, crystal structures, and In Vitro and In Vivo anticancer properties. European Journal of Medicinal Chemistry. Volume 281, 5 January 2025, 117007.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-155174Antiangiogenic agent 4
HY-160587Antiangiogenic agent 5
HY-147969Antiangiogenic agent 2
HY-168932Antiangiogenic agent 8
HY-169023Antiangiogenic agent 6
HY-149921Antiangiogenic agent 3
HY-146045Antiparasitic agent-7
HY-146103Antiproliferative agent-7
HY-170801Anticonvulsant agent 7
HY-147550Antitrypanosomal agent 7

Alternative Products

CatalogName
T79364-01Antiangiogenic agent 4
T62931-01Antiangiogenic agent 2
GTR19235663-01Antiangiogenic agent 5
GTR19212830-01Antiangiogenic agent 3
T201574-01Antiangiogenic agent 7
T200013-01Antiangiogenic agent 6
T205580-01Antiangiogenic agent 8
GTR19262817-01Antibacterial agent
GTR19211770-01Antiviral agent
TBI2469-5GMetformin HCl, Antidiabetic agent / Life extension agent

Popular Products