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Antiangiogenic agent 2

CAT: 0804-HY-147969Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147969Size:1 Each
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Description
Antiangiogenic agent 2 (compound 3b) is a potent thymidine phosphorylase inhibitor, with an IC50 of 39.71 μM. Antiangiogenic agent 2 shows anti-angiogenic activity[1].
CAS Number
2422149-84-4
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiangiogenic-agent-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(CC5=CC=CC=C5)=O)CC4)=C3)C1=O)OC
Molecular Formula
C26H26FN3O4
Molecular Weight
463.50
References & Citations
[1]Shahzad SA, et al. Synthesis, evaluation of thymidine phosphorylase and angiogenic inhibitory potential of ciprofloxacin analogues: Repositioning of ciprofloxacin from antibiotic to future anticancer drugs. Bioorg Chem. 2020 Jul;100:103876.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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