CVT-5440

CAT: 0804-HY-123038Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123038Size:1 Each
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Description
CVT-5440 is a xanthine based, selective, high affinity A2B adenosine receptors (AdoR) antagonist with a Ki of 50 nM (selectivity A1> 200; A2A>200; A3>167) . CVT-5440 has the potential for asthma research[1].
CAS Number
[531506-64-6]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cvt-5440.html
Smiles
O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=C(OCC4=NOC(C5=CC=CC(OC)=C5)=N4)C=C3)N2)C1=O
Molecular Formula
C27H28N6O5
Molecular Weight
516.55
References & Citations
[1]Jeff Zablocki, et al. The discovery of a selective, high affinity A (2B) adenosine receptor antagonist for the potential treatment of asthma.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A1 receptor (A1R) ; Adenosine A2A receptor (A2AR) ; Adenosine A2B receptor (A2BR)

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