CVT-5440

• Description :

  CVT-5440 is a xanthine based, selective, high affinity A2B adenosine receptors (AdoR) antagonist with a Ki of 50 nM (selectivity A1> 200; A2A>200; A3>167) . CVT-5440 has the potential for asthma research[1].

• UNSPSC :

  12352005

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cvt-5440.html

• Smiles :

  O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=C(OCC4=NOC(C5=CC=CC(OC)=C5)=N4)C=C3)N2)C1=O

• Molecular Formula :

  C27H28N6O5

• Molecular Weight :

  516.55

• References & Citations :

  [1]Jeff Zablocki, et al. The discovery of a selective, high affinity A (2B) adenosine receptor antagonist for the potential treatment of asthma.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Adenosine A1 receptor (A1R) ; Adenosine A2A receptor (A2AR) ; Adenosine A2B receptor (A2BR)

• CAS Number :

  [531506-64-6]