CVT-2759
CAT:
804-HY-123196
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CVT-2759
- CAS Number: 342419-09-4
- UNSPSC Description: CVT-2759 is a potent inhibitor of A1-ADOR, with the IC50 values of 0.18 μM and 9.5 μM to reduce the binding of [3H]CPX in the absence and presence of 1 mM GTP. CVT-2759 plays an important role in slowing AV nodal conduction and thereby ventricular rate without causing AV block, bradycardia, atrial arrhythmias, or vasodilation[1].
- Target Antigen: Adenosine Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/cvt-2759.html
- Smiles: O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N[C@H]4COCC4)O[C@@H]1COC(NC)=O
- Molecular Weight: 394.38
- References & Citations: [1]L Wu, et al. A partial agonist of the A1-adenosine receptor selectively slows AV conduction in guinea pig hearts. Am J Physiol Heart Circ Physiol. 2001 Jan;280(1):H334-43.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported