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CVT-313

CAT: 0804-HY-15339-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
CAT#:0804-HY-15339-01Size:10 mM - 1 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 with IC50 of 0.5 μM. CVT-313 inhibits CDC5L phosphorylation[1].
CAS Number
[199986-75-9]
Product Name Alternative
Cdk2 Inhibitor III
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cvt-313.html
Purity
99.90
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(N1C=NC2=C(NCC3=CC=C(OC)C=C3)N=C(N(CCO)CCO)N=C12)C
Molecular Formula
C20H28N6O3
Molecular Weight
400.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Graub R, et al. Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing. Cell Cycle. 2008 Jun 15;7 (12) :1795-803.|[2]Brooks EE, et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 1997 Nov 14;272 (46) :29207-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2; CDK4

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M17417-01CVT-313
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A15054-1CVT-313 1mg
A15054-100CVT-313 100mg
A15054-200CVT-313 200mg
A15054-25CVT-313 25mg
A15054-50CVT-313 50mg
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