CYP1B1-IN-4

• UNSPSC Description:

  CYP1B1-IN-4 is a 2,4-diarylthiazole compound with selectively CYP1B1 inhibition (IC50=0.2 nM). CYP1B1-IN-4 has little cytotoxicity and high stability in both human and rat liver microsomes[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cyp1b1-in-4.html

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles:

  COC1=CC=C(C(OC)=C1)C2=NC(C3=CC=C(C=C3)C#N)=CS2

• Molecular Weight:

  322.38

• References & Citations:

  [1]Hachey AC, et al. Design of Cytochrome P450 1B1 Inhibitors via a Scaffold-Hopping Approach. J Med Chem. 2022 Dec 15.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2685779-55-7