CYP1B1-IN-7
CAT:
804-HY-157942-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CYP1B1-IN-7
- CAS Number: 52601-58-8
- UNSPSC Description: CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 (IC50: 75 nM). CYP1B1-IN-7 also reverses resistance (IC50: 29 μM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel (HY-B0011)[1].
- Target Antigen: Cytochrome P450
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: cancer
- Assay Protocol: https://www.medchemexpress.com/cyp1b1-in-7.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC=C2C=CC=CC2=C1)/C=C/C3=CC=C(Cl)C=C3
- Molecular Weight: 292.76
- References & Citations: [1]Raju B, et al. Scaffold hopping for designing of potent and selective CYP1B1 inhibitors to overcome docetaxel resistance: synthesis and evaluation. J Biomol Struct Dyn. 2024 Feb 14:1-19.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported