CYP1B1-IN-2

• UNSPSC Description:

  CYP1B1-IN-2 (compound 9j) is a potent and selective CYP1B1 (cytochrome P450 1B1) inhibitor, with an IC50 of 0.52 nM[1].

• Target Antigen:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cyp1b1-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C2=CC=CC(C(F)(F)F)=C2)OC3=C1C=CC4=CC=CC=C43

• Molecular Weight:

  340.30

• References & Citations:

  [1]Dong J, et al. Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors. Eur J Med Chem. 2020 Feb 1;187:111938.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  727730-24-7