SHP2 protein degrader-2
CAT:
804-HY-145703-06
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SHP2 protein degrader-2
- CAS Number: 2740582-16-3
- UNSPSC Description: SHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells[1].
- Target Antigen: Phosphatase; PROTACs; SHP2
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;PROTAC;Protein Tyrosine Kinase/RTK
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/shp2-protein-degrader-2.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: ClC(C(SC1=NC=C(N2CCC(N)(CC2)C)N=C1N)=CC=C3)=C3NC(CCC(N(CC4)CCN4CCCCCCCCC(N[C@H](C(C)(C)C)C(N5[C@H](C[C@@H](C5)O)C(N[C@@H](C6=CC=C(C7=C(C)N=CS7)C=C6)C)=O)=O)=O)=O)=O
- Molecular Weight: 1115.89
- References & Citations: [1]Song Y, et al. Strategies Targeting Protein Tyrosine Phosphatase SHP2 for Cancer Therapy. J Med Chem. 2022 Feb 24;65(4):3066-3079.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported