SHP2 protein degrader-1

SHP2 protein degrader-1

• CAS Number: 2624181-69-5
• UNSPSC Description: SHP2 protein degrader-1 is a potent allosteric inhibitor of SHP2. SHP2 protein degrader-1 induces SHP2 degradation and cell apoptosis. SHP2 protein degrader-1 has the potential for researching SHP2 related diseases[1].
• Target Antigen: Apoptosis; Phosphatase; PROTACs; SHP2
• Type: Reference compound
• Related Pathways: Apoptosis;Metabolic Enzyme/Protease;PROTAC;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/shp2-protein-degrader-1.html
• Solubility: DMSO : 110 mg/mL (ultrasonic)
• Smiles: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCN4N=NC(CNC5(CCN(CC5)C6=CN=C(C7=C(Cl)C(Cl)=CC=C7)C(N)=N6)C)=C4)=CC=C3)=O)=O
• Molecular Weight: 908.83
• References & Citations: [1]Zheng M, et al. Novel PROTACs for degradation of SHP2 protein. Bioorg Chem. 2021;110:104788.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported