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(R) -Ketoprofen

CAT: 0804-HY-W322573-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W322573-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Ketoprofen is an orally active nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties. (R) -Ketoprofen does not significantly amplify the increase of inflammatory cytokines (such as tumor necrosis factor (TNF) and interleukin-1 (IL-1) ) induced by LPS, but it can inhibit the anti-inflammatory activity of (S) -Ketoprofen[1][2].
CAS Number
56105-81-8
UNSPSC
12352005
Hazard Statement
H302
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-ketoprofen.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H](C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
Molecular Formula
C16H14O3
Molecular Weight
254.28
Precautions
H302
References & Citations
[1]Estrada-Valenzuela D, et al. Lipase Assisted (S) -Ketoprofen Resolution from Commercially Available Racemic Mixture. Pharmaceuticals (Basel) . 2021 Sep 29;14 (10) :996. |[2]Ghezzi P, et al. Differential contribution of R and SIsomers in ketoprofen anti-inflammatory activity: role of cytokine modulation[J]. Journal of Pharmacology and Experimental Therapeutics, 1998, 287 (3) : 969-974.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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