Products for Research Use Only
RegisterLogin

Ketoprofen

CAT: 0804-HY-B0227-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0227-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2) . which is potential in the research of inflammation, immunology, and metabolic disease such as obesity[1][2][3].
CAS Number
22071-15-4
Product Name Alternative
RP-19583
UNSPSC
12352005
Hazard Statement
H301, H315, H319, H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Ketoprofen.html
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1)C2=CC=CC(C(C(O)=O)C)=C2
Molecular Formula
C16H14O3
Molecular Weight
254.28
Precautions
H301, H315, H319, H335
References & Citations
[1]Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12 (4) :533-7. |[2]NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472 (5) :583-596. |[3]Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101 (12) :11321-11329.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX-1; COX-2

Alternative Products

CatalogName
MBS340233-01Ketoprofen

Popular Products