17β-HSD1-IN-2

17β-HSD1-IN-2

• CAS Number: 1318265-18-7
• UNSPSC Description: 17β-HSD1-IN-2 (PBRM) is a non-estrogenic and steroidal covalent irreversible inhibitor of 17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) (Ki=368 nM). 17β-HSD1-IN-2 can be used for the research of estrogen-dependent disorders[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/17β-hsd1-in-2.html
• Smiles: O=C(N)C1=CC=CC(C[C@H]2C[C@@]3([H])[C@]4([H])CCC5=C(C=CC(CCBr)=C5)[C@@]4([H])CC[C@]3(C)[C@H]2O)=C1
• Molecular Weight: 496.48
• References & Citations: [1]Trottier A, et al. Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1. Biochem Pharmacol. 2017 Nov 15;144:149-161.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported