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17β-HSD10-IN-2

CAT: 0804-HY-155535Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155535Size:1 Each
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Description
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor, targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer[1].
CAS Number
2316765-79-2
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/17β-hsd10-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C(Cl)=C1)O)NC2=NC3=CC=C(C(O)=O)C=C3S2
Molecular Formula
C15H10ClN3O4S
Molecular Weight
363.78
References & Citations
[1]Benek O, et al. Development of submicromolar 17-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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