Myosin V-IN-1

CAT:

804-HY-152949-01

Size:

1 mg

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CAS Number: 1259177-59-7
UNSPSC Description: Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a Ki of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex[1][2].
Target Antigen: Myosin
Type: Reference compound
Related Pathways: Cytoskeleton
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/myosin-v-in-1.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(C1=CC(SCC2=CC(NC3=NC(NN=C4C5=CC=C(N6CCOCC6)C=C5)=C4C=N3)=CC=C2)=CC=C1)O
Molecular Weight: 538.62
References & Citations: [1]Maschi D, et al. Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses. Front Synaptic Neurosci. 2021 Apr 15;13:650334. |[2]Islam K, et al. A myosin V inhibitor based on privileged chemical scaffolds. Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8484-8.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-152949-03	Myosin V-IN-1
HY-152949-01	Myosin V-IN-1
HY-152949-02	Myosin V-IN-1
HY-163120	Myosin-IN-1
HY-162935	V-ATPase-IN-1
HY-162264	Tubulin polymerization/V-ATPase-IN-1
HY-161608	Myosin modulator 1
HY-112683-05	V-9302
HY-P5770	Jingzhaotoxin-V
HY-P2442	Bombolitin V

Cat	Name
SU2501	Sulphuric Acid 1 in 4 v/v - 1L
Ab1069	Anti-Myosin (Smooth) Antibody (Monoclonal, hSM-V)
AP85448	Myosin-1
AP86409	Myosin-1
AP86428	Myosin-1
AP85411-02	Myosin-1
MA1065	Anti-Myosin(Smooth) Antibody (monoclonal, hSM-V)
AP85598	Myosin-1
AP85411-01	Myosin-1
MBS5778096-02	PI3KD/V-IN-01