V-ATPase-IN-1

CAT: 0804-HY-162935-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-162935-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H+-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM) . V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides[1].

CAS Number

1243603-61-3

UNSPSC

12352101

Target

Proton Pump

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/v-atpase-in-1.html

Purity

99.23

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

ClC1=CC(CNC2=CC=CC=C2)=CC(OC)=C1OCC3=CC=CC=C3

Molecular Formula

C21H20ClNO2

Molecular Weight

353.84

References & Citations

[1]Lv B, et al. Discovery of the Chlorinated and Ammoniated Derivatives of Vanillin as Potential Insecticidal Candidates Targeting V-ATPase: Structure-Based Virtual Screening, Synthesis, and Bioassay[J]. Journal of Agricultural and Food Chemistry, 2024.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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