(Z)-10-Hydroxynortriptyline-d3

CAT:

804-HY-100646AS-02

Size:

1 mg

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UNSPSC Description: (Z)-10-Hydroxynortriptyline-d3 is the deuterium labeled (Z)-10-Hydroxynortriptyline (HY-100646A). (Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1][2].
Target Antigen: Drug Metabolite
Type: Isotope-Labeled Compounds
Related Pathways: Metabolic Enzyme/Protease
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Purity: 99.0
Solubility: 10 mM in DMSO
Smiles: OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C\CCNC([2H])([2H])[2H]
Molecular Weight: 282.40
References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

Cat	Name
HY-100646AS-01	(Z)-10-Hydroxynortriptyline-d3
HY-100646AS-02	(Z)-10-Hydroxynortriptyline-d3
HY-100646AS-03	(Z)-10-Hydroxynortriptyline-d3
HY-100646A-02	(Z)-10-Hydroxynortriptyline
HY-100646A-01	(Z)-10-Hydroxynortriptyline
HY-U00050S-01	(E)-10-Hydroxynortriptyline-d3
HY-U00050S-02	(E)-10-Hydroxynortriptyline-d3
HY-U00050-02	(E)-10-Hydroxynortriptyline
HY-U00050-01	(E)-10-Hydroxynortriptyline
HY-100646	(E)-10-Hydroxynortriptyline (maleate)