NG-497

• Description :

  NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].

• CAS Number :

  [2598242-66-9]

• UNSPSC :

  12352005

• Target :

  ATGL

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ng-497.html

• Concentration :

  10mM

• Purity :

  99.07

• Solubility :

  DMSO : 70 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC(OC)=CC(C2=CC=C(OCC)C=C2)=N1)OC(C)C

• Molecular Formula :

  C18H21NO4

• Molecular Weight :

  315.36

• References & Citations :

  [1]Gernot F Grabner, et al. Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes. J Am Chem Soc. 2022 Apr 13;144 (14) :6237-6250.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported