ORG 33628

• UNSPSC Description:

  ORG 33628 is a potent and selective progesterone receptor modulator. ORG 33628 shows anti-progestational and anti-glucocorticoid activity. ORG 33628 shows ovulation-inhibitory activity. ORG 33628 has the potential for the research of breast and endometrium[1][2].

• Target Antigen:

  Progesterone Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/org-33628.html

• Smiles:

  C[C@@]12[C@]3(C(CCO3)=C)CC[C@@]1([H])[C@@]4([H])C([C@@H](C5=CC=C(C=C5)C(C)=O)C2)=C6C(CC4)=CC(CC6)=O

• Molecular Weight:

  442.59

• References & Citations:

  [1]Kloosterboer HJ, et al. Preclinical experience with two selective progesterone receptor modulators on breast and endometrium. Steroids. 2000 Oct-Nov;65(10-11):733-40.|[2]Kloosterboer HJ, et al. Pharmacological properties of a new selective antiprogestagen: Org 33628. Ann N Y Acad Sci. 1995 Jun 12;761:192-201.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  155768-17-5