Xenin-8 (TFA)

Xenin-8 (TFA)

• UNSPSC Description: Xenin-8 TFA, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 TFA stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/xenin-8-tfa.html
• Solubility: H2O
• Smiles: O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](N)CC3=CNC=N3)=O)=O)=O)=O)N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CNC5=C4C=CC=C5.OC(C(F)(F)F)=O
• Molecular Weight: 1160.29
• References & Citations: [1]Ramona A Silvestre, et al. Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul Pept. 2003 Aug 15;115(1):25-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported