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CS-VIP 8 TFA

CAT: 0931-T207391-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207391-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase, JAK
Related Pathways
Stem Cells, Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
CS-VIP 8 TFA is a selective allosteric inhibitor of the WDR5 protein (Ki= 0.008 μM) . It induces a conformational change in the MLL1 complex, leading to the dissociation of MLL1 from the complex, thereby inhibiting the MLL1 histone methyltransferase activity and modulating HOX gene expression. CS-VIP 8 TFA shows potential for research in hematological disorders such as leukemia.
Molecular Formula
C45H53F7N12O9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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