BAM(8-22) (TFA)

BAM(8-22) (TFA)

• UNSPSC Description: BAM(8-22) TFA, a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner[1].
• Target Antigen: Mas-related G-protein-coupled Receptor (MRGPR)
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/bam-8-22-tfa.html
• Solubility: H2O
• Smiles: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](CC3=CNC4=CC=CC=C34)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H]5N(CCC5)C([C@H](CCCNC(N)=N)NC(CNC([C@@H](N)C(C)C)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
• References & Citations: [1]Parul Sikand, et al. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. J Neurosci. 2011 May 18;31(20):7563-7.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported