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Xenin-8

CAT: 0804-HY-P1257Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1257Size:1 Each
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Description
Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM) [1].
CAS Number
117442-28-1
UNSPSC
12352209
Target
Insulin Receptor; Neurotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/xenin-8.html
Solubility
H2O
Smiles
O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](N)CC3=CNC=N3)=O)=O)=O)=O)N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CNC5=C4C=CC=C5
Molecular Formula
C51H79N15O9
Molecular Weight
1046.27
References & Citations
[1]Ramona A Silvestre, et al. Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul Pept. 2003 Aug 15;115 (1) :25-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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