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ELA-32 (human) (TFA)

CAT: 0804-HY-P2196A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2196A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ELA-32 (human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM) . ELA-32 (human) TFA exhibits no binding GPR15 and GPR25. ELA-32 (human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32 (human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32 (human) TFA stimulates angiogenesis in HUVEC cells.
UNSPSC
12352209
Target
Apelin Receptor (APJ)
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ela-32-human-tfa.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[QRPVNLTMRRKLRKHNCLQRRCMPLHSRVPFP(Disulfidebridge:Cys17-Cys22)(TFAsalt)]
Molecular Formula
C170H289N63O39S4.xC2HF3O2
Molecular Weight
3967.82 (free acid)
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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