GCSF Receptor Recombinant Rabbit Monoclonal Antibody [PSH03-44]

GCSF Receptor Recombinant Rabbit Monoclonal Antibody [PSH03-44]

• Description: The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belong to a family of cytokine receptors known as the hematopoietin receptor family. The granulocyte colony-stimulating factor receptor is present on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2.
• Product Name Alternative: CD 114 antibody CD114 antibody CD114 antigen antibody Colony stimulating factor 3 receptor (granulocyte) antibody Colony stimulating factor 3 receptor antibody CSF 3R antibody CSF3R antibody CSF3R_HUMAN antibody Csfgr antibody G CSF R antibody G-CSF receptor antibody G-CSF-R antibody GCSFR antibody Granulocyte colony stimulating factor receptor antibody Granulocyte colony-stimulating factor receptor antibody OTTHUMP00000009703 antibody OTTHUMP00000009704 antibody OTTHUMP00000009705 antibody
• Abbreviation: CSF3R, GCSFR
• CAS Number: 9000-83-3
• Swiss Prot: Q99062 Human, P40223 Mouse,
• Cellular Locus: Cell membrane; Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human GCSF Receptor aa 651-836 / 836.
• Isotype: IgG
• Clone: PSH03-44
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: A431 cell lysate, K-562 cell lysate, THP-1 cell lysate, Jurkat cell lysate, Ramos cell lysate, mouse placenta tissue lysate, mouse brain tissue lysate, mouse testis tissue lysate, rat placenta tissue lysate, rat brain tissue lysate, rat testis tissue lysate, rat skin tissue lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 92 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes