67kDa Laminin Receptor Recombinant Rabbit Monoclonal Antibody [JF0955]

67kDa Laminin Receptor Recombinant Rabbit Monoclonal Antibody [JF0955]

• Description: Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellular matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregulated in aggressive carcinoma. The precursor, which is also identified as p40 ribosome-associated protein, appears to be a multifunctional protein involved in the translational machinery. Laminin-R (also known as colon carcinoma laminin-binding protein) and is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Additionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.
• Product Name Alternative: 34/67 kDa laminin receptor antibody 37 kDa laminin receptor precursor antibody 37/67 kDa laminin receptor antibody 37LRP antibody 40S ribosomal protein SA antibody 67 kDa laminin receptor antibody 67LR antibody Colon carcinoma laminin binding protein antibody Colon carcinoma laminin-binding protein antibody LAMBR antibody Laminin receptor 1 antibody Laminin-binding protein precursor p40 antibody LAMR 1 antibody LamR antibody LAMR1 antibody LBP antibody LBP/p40 antibody LRP antibody LRP/LR antibody Multidrug resistance associated protein MGr1 Ag antibody Multidrug resistance associated protein MGr1Ag antibody Multidrug resistance-associated protein MGr1-Ag antibody NEM/1CHD4 antibody p40 antibody Ribosomal Protein SA antibody rpsA antibody RSSA_HUMAN antibody SA antibody
• Abbreviation: 37LRP, LRP/LR, 67LR, LamR, LBP/p40, RPSA
• CAS Number: 9000-83-3
• Swiss Prot: P08865 Human, P14206 Mouse, P38983 Rat
• Cellular Locus: Cell membrane, Nucleus, Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human 67kDa Laminin Receptor aa250-295 / 295.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
• Positive Control: K562 cell lysate, HepG2 cell lysate, A431 cell lysate, Hela, MCF-7, HepG2, RH-35, mouse brain tissue, mouse kidney tissue, human stomach carcinoma tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 33 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes