BCL-XL-IN-1

• UNSPSC Description:

  BCL-XL-IN-1 (Compound 11) is a selective BCL-XL inhibitor with a Ki of L TR-FERT. BCL-XL-IN-1 can be used in cancer research[1].

• Target Antigen:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcl-xl-in-1.html

• Smiles:

  CC1=C(C=NN1C[C@]2(CC3(C)C4)C[C@](OCCNCC[C@H](O)CO)(C3)CC4(C)C2)C(C(C(O)=O)=N5)=CC=C5N6CCC7=C(C6)C(C(NC(S8)=NC9=C8C=CC=C9)=O)=CC=C7

• Molecular Weight:

  834.04

• References & Citations:

  [1]Judd AS, et al. BCL-XL-targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechanism toxicity of small-molecule inhibitors. Sci Adv. 2024 Oct 4;10(40):eado7120.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported