PROTAC Bcl-xL degrader-2
CAT:
804-HY-139309-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC Bcl-xL degrader-2
- CAS Number: 2920415-08-1
- UNSPSC Description: PROTAC Bcl-xL degrader-2 is a potent Bcl-xL (Bcl-2 family member) degrader based on von Hippel-Lindau ligand, with an IC50 of 0.6 nM.
- Target Antigen: Bcl-2 Family; PROTACs
- Type: Reference compound
- Related Pathways: Apoptosis;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-bcl-xl-degrader-2.html
- Smiles: O=C(C1=C(CCCOC2=CC=C(C#CCOCCOCCOCCOCCOCCOCCC(N[C@H](C(N3[C@H](C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)C[C@@H](O)C3)=O)C(C)(C)C)=O)C=C2)SC(N6CC7=C(C=CC=C7C(NC8=NC9=CC=CC=C9S8)=O)CC6)=N1)O
- Molecular Weight: 1329.60
- References & Citations: [1]Chun-Wa Chung, et al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.
- Shipping Conditions: Room Temperature