HDHODH-IN-3

CAT: 0804-HY-135570-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-135570-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HDHODH-IN-3 (compound 21d) is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6[1].

CAS Number

1644156-80-8

UNSPSC

12352005

Target

Dihydroorotate Dehydrogenase; DNA/RNA Synthesis; Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dhodh-in-2.html

Purity

99.97

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

CCC1=CN=C(N2N=C(OCC)C(OC3=CC=CC=C3Br)=C2C)N=C1

Molecular Formula

C18H19BrN4O2

Molecular Weight

403.27

References & Citations

[1]Lucas-Hourani M, et al. Original 2- (3-Alkoxy-1H-pyrazol-1-yl) azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH) .J Med Chem. 2015 Jul 23;58 (14) :5579-98.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
T11025-01	HDHODH-IN-3
BA7298-5	hDHODH-IN-13
BA4054-10	hDHODH-IN-1
T88973-01	HDHODH-IN-15
T63238-01	hDHODH-IN-8
T11031-01	HDHODH-IN-7
MBS5815189	hDHODH-IN-11
BUP16207-01	HDHODH-IN-4
GTR19176806-01	HDHODH-IN-5
MBS5805712	hDHODH-IN-10

HDHODH-IN-3

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