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HDHODH-IN-15

CAT: 0931-T88973-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88973-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis, Dehydrogenase
Related Pathways
Metabolism, Apoptosis
Bioactivity
HDHODH-IN-15 (Compound H19) acts as an inhibitor of human dihydroorotate dehydrogenase (hDHODH), demonstrating an IC50 of 0.21 μM. It exhibits cytotoxic effects in cancer cells such as NCI-H226, HCT-116, and MDA-MB-231, with IC50 values ranging from 0.95 to 2.81 μM. Furthermore, hDHODH-IN-15 induces ferroptosis in HCT-116 cells and shows antitumor activity.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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