MMP13 Fluorogenic Assay Kit

CAT: 0421-79991Size: 96 ReactionsDry Ice: YesHazardous: No
CAT#:0421-79991Size:96 Reactions
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MMP13 (matrix metalloproteinase 13), also known as collagenase 3, is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix. MMP13 primarily cleaves type II collagen, and it is expressed in the skeleton where it plays a role in restructuring the collagen matrix for bone mineralization and cartilage turnover. MMP13 is also overexpressed in rheumatoid arthritis, osteoarthritis, and many human carcinomas, suggesting its potential as a therapeutic target.
Description
The Fluorogenic MMP13 Assay Kit is designed to measure MMP13 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.Need us to run inhibitor screens or profile your compounds against MMP13? Check out ourProtease Screening Services.
UniProt
P45452
Format
CatalogNumberComponentAmountStorage11345MMP13, His-tag4 µg-80°CAvoidfreeze/thawcycles!79919Fluorogenic MMP Substrate (1 mM) 10 µl-80°C799171X MMP Assay Buffer 125 ml-20°C79685Black, low binding black microtiter plate1RoomTemp
Shipping Conditions
-80°C
Storage Conditions
At least 6 months from date of receipt when stored as directed.

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