Products for Research Use Only
RegisterLogin

MMP7 Fluorogenic Assay Kit

CAT: 0421-78864Size: 96 ReactionsDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0421-78864Size:96 Reactions
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
MMP7 (also known as matrix metalloproteinase 7 or pump-1 protease) is a member of the large family of matrix metalloproteinases (MMP) responsible for the breakdown of extracellular matrix proteins such as casein, collagen, and fibronectin. Most MMPs are secreted as inactive pro-proteins and are activated when cleaved by other extracellular proteinases. MMP7 cleaves fibronectin, gelatin and elastin, but not collagen. MMPs are involved in tissue remodeling and in the escape of metastatic cells from the primary tumor and angiogenesis. MMP7 can activate MMP2 and MMP9, and upregulation of MMP7 is found in many carcinomas. They are candidate therapeutic targets in various diseases related to tissue remodeling including cancer and inflammatory diseases.
Description
The MMP7 (Matrix MetalloProteinase 7) Fluorogenic Assay Kit is designed to measure MMP7 protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.Need us to run inhibitor screens or profile your compounds against MMP7? Check out ourProtease Screening Services.
UniProt
P09237
Applications
Screen or profile small molecule inhibitors of MMP7.
Format
Catalog #NameAmountStorageRecombinant MMP7*7.5 µg-80°C799191 mM MMP Substrate10 µl-80°C79917MMP Assay Buffer 125 ml-20°C79685Black 96-well plate1Room Temp*The concentration of the protein is lot-specific and will be indicated on the tube.
Shipping Conditions
-80°C
Storage Conditions
This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
Notes
Troubleshooting GuideVisitbpsbioscience.com/assay-kits-faqfor detailed troubleshooting instructions. For further questions, please email[email protected]
Contraindications
The final concentration of DMSO in the assay should not exceed 1%.

UniProtKB · P09237

Matrilysin

MMP7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09237
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MMP7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.24.23
Processing
Precursor
Secondary accessions
Q9BTK9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMetal-bindingZinc

Biological process

Collagen degradation

Cellular component

Extracellular matrixSecreted

Molecular function

HydrolaseMetalloproteaseProtease

Domain

Signal

PTM

Zymogen

Related Products

CatalogName
79983MMP1 Fluorogenic Assay Kit
79918MMP2 Fluorogenic Assay Kit
79929MMP8 Fluorogenic Assay Kit
79915MMP9 Fluorogenic (Q279R) Assay Kit
78858-1PARG Fluorogenic Assay Kit
82165GPX4 Fluorogenic Assay Kit
82158ARH3 Fluorogenic Assay Kit
82154Sialidase Fluorogenic Assay Kit
50687HDAC11 Fluorogenic Assay Kit
50065HDAC5 Fluorogenic Assay Kit

Alternative Products

CatalogName
GWB-PS1C2AHDAC4 Fluorogenic Assay Kit
GWB-PSF8DDHDAC1 Fluorogenic Assay Kit
GWB-PS5DD4HDAC5 Fluorogenic Assay kit
GWB-PSFEF5HDAC3 Fluorogenic Assay kit
GWB-PS1799HDAC7 Fluorogenic Assay Kit
GWB-PS7C2FHDAC6 Fluorogenic Assay kit
GWB-4C8F93HDAC Fluorogenic Assay Kit
GWB-2FFDA0Fluorogenic GCN5 Assay Kit
GWB-PS3366HDAC2 Fluorogenic Assay Kit
GWB-47F4E7HDAC8 Fluorogenic Assay Kit

Popular Products