MMP14 Fluorogenic Assay Kit

CAT: 0421-79993Size: 96 ReactionsDry Ice: YesHazardous: No
CAT#:0421-79993Size:96 Reactions
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MMP14 (matrix metalloproteinase 14) is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix.MMP14 regulates the activity of multiple extracellular and plasma membrane proteins, influencing cell-cell and cell-extracellular matrix (ECM) degradation and remodeling, cell invasion, and cancer metastasis. MMP14 is highly expressed in most sarcomas, and levels of MMP14 correlate with breast cancer progression. Upregulation of MMP14 also promotes glioma invasion and tumor cell proliferation and plays a role in angiogenesis.
Description
The Fluorogenic MMP14 Assay Kit is designed to measure MMP14 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.Need us to run inhibitor screens or profile your compounds against MMP14? Check out ourProtease Screening Services.
UniProt
P50281
Format
CatalogNumberComponentAmountStorage100585MMP14, His-tag7 µg-80°CAvoidfreeze/thawcycles!79919Fluorogenic MMP Substrate (1 mM) 10 µl-80°C799171X MMP Assay Buffer 125 ml-20°C79685Black, low binding black microtiter plate1RoomTemp
Shipping Conditions
-80°C
Storage Conditions
At least 6 months from date of receipt when stored as directed.

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